Vancomycin-Resistant Enterococcal Endophthalmitis

Vancomycin-resistant enterococcal endophthalmitis.

V ancomycin-sensitive enterococcal acute endophthalmitis has been reported following cataract extraction, penetrating keratoplasty, trabeculectomy, and pupilloplasty. However, vancomycinresistant enterococcal (VRE) endophthalmitis has been described in only 3 patients to date: an immunocompromised, hospitalized patient with underlying bacteremia, an immunocompetent patient following keratoplast...

Post-traumatic vancomycin-resistant enterococcal endophthalmitis

The emergence of antibiotic-resistant organisms among severe ocular infections is of grave concern. We describe the first reported case of vancomycin-resistant enterococcal endophthalmitis following ocular trauma, uniquely caused by Enterococcus gallinarum. The organism demonstrated intrinsic resistance to ceftazidime and vancomycin but responded favorably to a combination of intravitreal and i...

Vancomycin-resistant enterococcal infections: epidemiology, clinical manifestations, and optimal management

Since its discovery in England and France in 1986, vancomycin-resistant Enterococcus has increasingly become a major nosocomial pathogen worldwide. Enterococci are prolific colonizers, with tremendous genome plasticity and a propensity for persistence in hospital environments, allowing for increased transmission and the dissemination of resistance elements. Infections typically present in immun...

Daptomycin for the treatment of vancomycin-resistant enterococcal infections.

Quinupristin/dalfopristin: therapeutic potential for vancomycin-resistant enterococcal infections.

Vancomycin-resistant Enterococcus faecium (VREF) is an opportunistic pathogen, which causes infections among severely ill, hospitalized patients, in whom it is likely to increase the risk of progressive local or systemic disease and to worsen the prognosis. Because these organisms are often highly resistant to penicillin, ampicillin and many other antimicrobials including the glycopeptides, the...